Research Assoicate - Bioanalytical Chemistry

Apply for Job with Amicus Therapeutics

Description
Research Associate (Bioanalytical Chemistry) – Drug Development

Amicus Therapeutics is a biopharmaceutical company developing novel, oral therapeutics known as pharmacological chaperones for the treatment of a range of human genetic diseases. Pharmacological chaperone technology involves the use of small molecules to restore or improve biological activity in cells by selectively binding to misfolded proteins caused by genetic mutations. Amicus is initially targeting lysosomal storage disorders, which are severe, chronic genetic diseases with unmet medical needs. Amicus is currently conducting Phase 2 clinical trials for its lead compound, AT1001, for Fabry disease, has completed Phase 1 clinical trials of AT2101 for Gaucher disease and is conducting Phase 1 clinical trials of AT2220 for Pompe disease.

The company is headquartered in Cranbury, NJ. Amicus has a fast-paced, high-energy, entrepreneurial team environment where employees are encouraged to be innovative and resourceful. Amicus seeks high-caliber, talented individuals with a passion to succeed. Additional information on the company, product pipeline, and technology is available at www.amicustherapeutics.com.


Responsibilities

* Hands-on responsibility for all aspects of bioanalytical work to support the Company's development portfolio of small molecule therapeutics and biomarkers.
* Responsibility for various stages of LC-MS/MS assay development and application in the quantitation of drug and metabolite concentrations in body fluids and tissue samples that will support the internal discovery operation.
* Activities to include method development and validation for active drug and PD markers.
* Compile data and write protocols and reports. Communicate analytical data across scientific departments.
* Proficient in the use of automated sample preparation techniques. Ability to use standard word processing and spreadsheet applications in the finalization and reporting of final results.
* Calibrate and maintain MS instrumentation. Evaluate new and emerging analytical technology in support of development projects.
* Establish and implement laboratory systems that maximize efficiency and regulatory compliance in a growing analytical laboratory.
* Interact closely with Regulatory Affairs providing summary data and reports required for regulatory submissions.

Requirements
Education & Requirements
Our environment requires that the candidate be both a hands-on innovative scientist and an effective project manager. The candidate should have a B.S or MS in analytical chemistry or a related field with 6-8 years of relevant experience in quantitative bioanalytical techniques involving the extraction and analysis of small molecules and biomarkers from biological samples including tissue samples. Candidate should have extensive hands-on experience using the Sciex LC/MS platforms and have a thorough understanding of GLPs. Proficiency with personal computer applications for word processing, spreadsheets and graphics, as well as good oral and written communication skills are desirable. Technical writing ability and familiarity with regulatory submissions (IND, NDA, CTD format) is preferred.

Scientist

Apply for Job with Southwest Research Institute


Description
Scientist (General Chemistry)

Responsibilities of Scientist includes:

* Perform various wet chemistry methods using gravimetric, titrimetric, and spectrophotometric techniques including EPA / SW-846 / ASMT / OSHA / NIOSH/ APHA

* Run a variety of instrumental methods including atomic absorption, atomic emission, mass spectrometric, and radiochemical.

Requirements
Scientist (General Chemistry)

Requirements of Scientist includes:

* Requires a BS in Physical Sciences, Chemistry preferred, and minimum 1 year experience in the methods listed above.

* Good math and computer skills and general laboratory knowledge required.

* Must be willing to work overtime and weekends if necessary; be able to assist with data reports concerning test results, and develop procedures to perform analysis.

* Must be able to work under a stressful environment.

Electro-Chemistry Engineer

Apply for Job with AVX Corporation

Description
MS degree in Electrochemistry / Chemical engineering / Chemistry or Materials Science is required. The candidate should have at least 8 years of industrial experience in the aluminum electrolytic capacitor industry. A BS degree with 10 years industrial experience will be considered. The candidate should possess a working knowledge of wet aluminum capacitors including:
• Anodes
• Cathodes
• Electrolyte chemistry
• Can and stopper assembly
• Analysis of corresponding electrical characteristics and related physical phenomenon and failure mechanisms a definite plus.
Experience in new product testing and development is required.
Knowledge of capacitors and varistors performance required. Job is to lead characterization efforts and development of new test methodologies. Additional duties involve conducting theoretical and experimental investigations in a research setting.

Requirements
MS degree in Electrochemistry / Chemical engineering / Chemistry or Materials Science is required. The candidate should have at least 8 years of industrial experience in the aluminum electrolytic capacitor industry. A BS degree with 10 years industrial experience will be considered.

Chemical Engineer

Apply for Job at Kelly Scientific Resources

Description
The successful candidate will carry out modeling research on projects related to automotive/environmental catalysis. Responsibilities include kinetic and reactor modeling of heterogeneous catalytic systems, kinetic experimentation, optimization, data analysis and reporting, and computer programming. In addition to performing research on assigned projects the candidate is expected to interact effectively with other scientists, application engineers, and business people within the corporation. Occasional customer interactions such as presentations will also be required.

Qualifications
Ph.D. in chemical engineering or chemistry with 2-5 years industrial or post-doctoral experience in kinetic and/or reactor modeling of heterogeneous catalytic systems. Programming abilities and hands on experience with catalytic reactors is desired. Candidate must have good interpersonal and communication skills and work well in the team environment. Candidate must display initiative and have a strong drive for results, while always showing respect for safety and quality.
Locations United States-New Jersey-Iselin

Schedule Full-time
Job Type Standard
Shift Day Job
Travel Yes, 5 % of the Time

Developmental Biology PhD Scientist

Apply for Job with Aderans Research Institute

Description

Environment:

· Early stage company backed by a major international firm.

· Exciting, high-paced opportunity.

· Leader in bioengineered solutions for hair regeneration.



Responsibilities and duties:

· Identify and organize research projects in the area of developmental biology, organogenesis and regeneration.

· Manage a team of scientists participating in the research

· Write progress reports on the research

· Prepare and deliver formal reports on the research

· Do hands on work in association with the team

· Have a command of the modern tools of molecular and cellular biology

· Teach and mentor a research team

· Interact with other individuals and teams in the laboratory

· Keep abreast of scientific progress in the field of research

· Interact with the world community of scientists in the field

· Write formal reports for peer review and publication

Requirements

Education:

· PhD in the general field of developmental biology, organogenesis, regeneration. Post doctoral experience of at least 5 years.

Work experience:

· Minimum five (5) years in a research laboratory showing independent work in the field

· Record of publications documenting productivity in the field

· Demonstrated ability to work in a fast paced research laboratory environment of a biotechnology start-up.

· Demonstrated ability to work in a group

· Industrial research experience would be attractive as GLP usage is needed.

Exposure:

· Human and laboratory animal (mouse, rat, pig) tissues.

· Laboratory chemicals and reagents typically used in cell and molecular biology.

Travel:

Less than 10% of time in travel.

Hire:

Full-time, regular

Reporting structure:


Philadelphia position. Reports to senior scientist
Contact:

K Stenn, Aderans Research Institute

Post-Doc Research Associate

Apply for Job with Children's Memorial Hospital

Description
Tumor suppression and basement membranes.

A post-doctoral position is available immediately for a new project, recently funded by NCI, to dissect the role of a newly identified tumor suppressor. Highly motivated post-doctoral scientists with quality doctoral and/or post-doctoral research experience and a good publication record are invited to apply. The successful candidate will have proven skills in molecular biology, cell biology and protein biochemistry. Expertise in the analysis of basement membrane components would be a definite advantage.

Requirements
The research will take place in the Children’s Memorial Research Center laboratories in Lincoln Park, which provide an outstanding research environment. Successful applicants will be eligible for post-doctoral appointments in the Department of Pediatrics, Feinberg School of Medicine, Northwestern University. The post is available for 2 years in the first instance.

For further information please see: http://www.childrensmrc.org/harris/
Please email letter of application, CV and the names of 3 referees to
[Click here for email]. Refer to CMRC/HMG/Harris

Post-Doc - Microbial Physiology

Apply for job with Princeton University

Description
Princeton University is a vibrant community of scholarship and learning that stands in the nation's service and in the service of all nations. Chartered in 1746, and known as the College of New Jersey until 1896, it was British North America's fourth college.

Position Summary: Post-doctoral positions are available at Princeton University in the area of bioenergy to join a DOE-funded interdisciplinary team studying microbial hydrogen production from a quantitative perspective. Participating labs include Rabinowitz (metabolomics), Dismukes (photosynthesis) and Rabitz (quantitative modeling).

Job Function: Regular Professional Research

Grade: RR 040

Eligible for Overtime: No

Requirements
Essential Qualifications: Candidates are preferred with experience in cellular metabolism, microbial physiology, systems biology, mass spectrometry, instrument development, and/or computational chemistry. Exceptional opportunities are available for highly motivated candidates with strong publication records, regardless of their specific area of expertise. Applicants should recently have received their Ph.D. Rank and salary are dependent upon qualifications. Applications should include a curriculum vitae that includes a list of publications and a brief statement (3 pages) of research interests and goals. On the application form, please give three references that you have asked to send letters of recommendation. Reference letters should be sent to the address below. All other materials must be submitted through the website. Send reference letters only to: Bioenergy postdoc 249 Carl Icahn Laboratory Princeton University, Princeton, NJ 08544-1014

Education Required: Doctorate Degree

Post-Doc - Pathology

Apply for Job at Thomas Jefferson:


Description
Honored by HealthGrades with the Distinguished Hospital Award for Clinical Excellence, Thomas Jefferson University Hospital combines outstanding medical education, innovative research, and world-class patient care. By continually improving the quality of services we offer, our employees discover an exemplary clinical setting—one where advanced learning goes hand in hand with renowned caring. For the eighth consecutive year, Jeff was granted the Consumer Choice Award for innovation by the National Research Corporation, recognition not only of the work we do, but the people we hire.

We currently have two FT (80 hours biweekly) postdoctoral positions available in proteoglycan research, cancer and angiogenesis. The post doctoral fellows will investigate the biology of perlecan and endorepellin in vertebrate (zebrafish) vascular development and tumor angiogenesis. The candidates will join a multidisciplinary team of researchers involved in investigating the molecular mechanisms through which perlecan and its angiostatic, C-terminal fragment endorepllin affect the development of new blood vessels both in vitro and in vivo.

Requirements
# Ph.D or an M.D./Ph.D. in biochemistry or cell biology.
# A molecular background is highly desirable.
# Experience with zebra fish and image analysis is welcome, but not necessary.

Send Resumes and three letters of reference to:
Renato V. Iozzo, M.D.
Department of Pathology, Anatomy & Cell Biology
Cancer Cell Biology & Signaling Program
Thomas Jefferson University
1020 Locust Street, Room 249 JAH
Philadelphia, PA 19107-6799, U.S.A
Fax: 215-923-7969

Princeton Post-Doc

Apply for job at Princeton

Description
Princeton University is a vibrant community of scholarship and learning that stands in the nation's service and in the service of all nations. Chartered in 1746, and known as the College of New Jersey until 1896, it was British North America's fourth college.

Position Summary: A postdoctoral position is available in the Neuroscience of Cognitive Control Laboratory of Dr. Jonathan Cohen, in the Department of Psychology and the Center for the Study of Brain, Mind and Behavior at Princeton University. The research project combines computational/mathematical modeling with behavioral and neuroimaging experiments to study the brain mechanisms of decision making, reinforcement, and performance optimization.

Job Function: Regular Professional Research

Grade: RR 040

Eligible for Overtime: No

Requirements
Essential Qualifications: Ph.D. in psychology, neuroscience, or closely related field; strong background with fMRI.

Education Required: Doctorate Degree