Research Associate
Research Associate Amicus Therapeutics
Description
Amicus Therapeutics is a biopharmaceutical company developing novel, oral therapeutics known as pharmacological chaperones for the treatment of a range of human genetic diseases. Pharmacological chaperone technology involves the use of small molecules to restore or improve biological activity in cells by selectively binding to misfolded proteins caused by genetic mutations. Amicus is initially targeting lysosomal storage disorders, which are severe, chronic genetic diseases with unmet medical needs. Amicus is currently conducting Phase 2 clinical trials for its lead compound, AT1001, for Fabry disease, has completed Phase 1 clinical trials of AT2101 for Gaucher disease and is conducting Phase 1 clinical trials of AT2220 for Pompe disease.
Amicus is funded by some of the most preeminent venture capital firms in health care, including New Enterprise Associates, Prospect Ventures, Frazier Health Care Ventures, Quaker Bioventures, CHL Medical and Canaan Partners. The company has built a first rate senior management team with a significant track record of success in this industry.
The company is headquartered in Cranbury, NJ. Amicus has a fast-paced, high-energy, entrepreneurial team environment where employees are encouraged to be innovative and resourceful. Amicus seeks high-caliber, talented individuals with a passion to succeed. Additional information on the company, product pipeline, and technology is available at www.amicustherapeutics.com.
Responsibilities:
Our state-of-the art laboratory uses a combination of cell-biology, genetic, and biochemical approaches to study neurodegenerative diseases caused by defects in protein folding. In this position, the Research Associate will have responsibilities including but not limited to: mammalian cell culture; cell transfection, maintenance of cell lines, cell-based experiments; plate-based assays; plasmid construction and amplification; protein purification & biochemical characterization; write reports and prepare slide presentations.
Requirements
Requirements/Qualifications:
A BS in biology and 3+ years of laboratory experience, or MS with 1+ year of laboratory experience is required. The successful candidate will have proven cell and molecular biology skills, including experience with culturing and transfecting mammalian cells, designing and constructing plasmids, PCR, qRT-PCR, fluorescent plate-based assays, and basic protein purification and characterization by SDS-PAGE. Strong interpersonal, oral and written communication skills are imperative. The candidate will have exceptional record-keeping skills and show attention to detail when conducting experiments. Exhibiting a sense of urgency and the ability to work under tight deadlines is a must. The candidates must be able to demonstrate initiative, innovative thinking, and the ability to work collaboratively with other scientists in a fast-paced and rapidly-changing team environment.
Amicus Therapeutics offers a competitive compensation and benefits package including, medical, dental, disability, life insurance, flexible spending accounts, 401k and stock options.
Qualified candidates please submit your résumé to:
Email: [Click here for email]
Fax: 609-662-2099
Amicus Therapeutics is an equal opportunity employer.
NO PHONE CALLS PLEASE
NO AGENCIES PLEASE
Description
Amicus Therapeutics is a biopharmaceutical company developing novel, oral therapeutics known as pharmacological chaperones for the treatment of a range of human genetic diseases. Pharmacological chaperone technology involves the use of small molecules to restore or improve biological activity in cells by selectively binding to misfolded proteins caused by genetic mutations. Amicus is initially targeting lysosomal storage disorders, which are severe, chronic genetic diseases with unmet medical needs. Amicus is currently conducting Phase 2 clinical trials for its lead compound, AT1001, for Fabry disease, has completed Phase 1 clinical trials of AT2101 for Gaucher disease and is conducting Phase 1 clinical trials of AT2220 for Pompe disease.
Amicus is funded by some of the most preeminent venture capital firms in health care, including New Enterprise Associates, Prospect Ventures, Frazier Health Care Ventures, Quaker Bioventures, CHL Medical and Canaan Partners. The company has built a first rate senior management team with a significant track record of success in this industry.
The company is headquartered in Cranbury, NJ. Amicus has a fast-paced, high-energy, entrepreneurial team environment where employees are encouraged to be innovative and resourceful. Amicus seeks high-caliber, talented individuals with a passion to succeed. Additional information on the company, product pipeline, and technology is available at www.amicustherapeutics.com.
Responsibilities:
Our state-of-the art laboratory uses a combination of cell-biology, genetic, and biochemical approaches to study neurodegenerative diseases caused by defects in protein folding. In this position, the Research Associate will have responsibilities including but not limited to: mammalian cell culture; cell transfection, maintenance of cell lines, cell-based experiments; plate-based assays; plasmid construction and amplification; protein purification & biochemical characterization; write reports and prepare slide presentations.
Requirements
Requirements/Qualifications:
A BS in biology and 3+ years of laboratory experience, or MS with 1+ year of laboratory experience is required. The successful candidate will have proven cell and molecular biology skills, including experience with culturing and transfecting mammalian cells, designing and constructing plasmids, PCR, qRT-PCR, fluorescent plate-based assays, and basic protein purification and characterization by SDS-PAGE. Strong interpersonal, oral and written communication skills are imperative. The candidate will have exceptional record-keeping skills and show attention to detail when conducting experiments. Exhibiting a sense of urgency and the ability to work under tight deadlines is a must. The candidates must be able to demonstrate initiative, innovative thinking, and the ability to work collaboratively with other scientists in a fast-paced and rapidly-changing team environment.
Amicus Therapeutics offers a competitive compensation and benefits package including, medical, dental, disability, life insurance, flexible spending accounts, 401k and stock options.
Qualified candidates please submit your résumé to:
Email: [Click here for email]
Fax: 609-662-2099
Amicus Therapeutics is an equal opportunity employer.
NO PHONE CALLS PLEASE
NO AGENCIES PLEASE
Labels: Reasearch+Associate, Scientist
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